In the next 50 years, the key issues in Chinese business will no longer focus on the performance of individual enterprises, but on identifying those companies that are transforming traditional industry operations. In the new cycle driven by technology, they are using technology, data, and unique ecosystems to recreate new business values.
Over the past few decades, global business has undergone several profound changes, including digitization, globalization, and restructuring of industrial chains. In the new technological cycle and geopolitical economic environment, growth remains important, but its quality, resilience, and sustainability have become new criteria for measuring corporate value. Today, the challenge for global business is not just about growth, but how to continuously create long-term value in a highly competitive and uncertain environment. Whether companies can build the ability to endure through cycles, convert technological innovation into industrial competitiveness, and maintain adaptability during industrial restructuring and global value chain reconfiguration, has become the new focus of competition.
Chinese enterprises are at a critical turning point in this transformation. Big Data & AI is gradually evolving from a technical tool into a new infrastructure for social and economic development. The manufacturing industry is shifting from scale advantages to overall system efficiency. Large consumer sectors are reshaping demand through service-oriented, downward-focused, and low-carbon approaches. Healthcare has entered a new stage centered on innovation and globalization. Semiconductors are moving from strengthening chain links to system collaboration. These changes occur not independently; in deep business transformations, the advantages of Chinese enterprises are shifting from single capabilities to the construction of overall system capabilities.
Under this context, Frost & Sullivan and FT Chinese Network jointly released "Top Ten Business Cases That Will Impact the Next 50 Years" (hereinafter referred to as "The Top Ten Cases"). On August 4, at the opening ceremony of the 20th Frost & Sullivan Global Growth, Innovation & Leadership Summit, Ms. Zhang Yan, publisher of FT Chinese Network, and Dr. Wang Xin, Senior Vice President of Frost & Sullivan, Asia-Pacific Co-Chair, and Chairman of China, jointly released "Top Ten Business Cases That Will Impact the Next 50 Years".

The 10 enterprise cases selected this time are based on the fifth issue of Frost & Sullivan's "White Paper on Industrial Development Trends in China for the Next 50 Years", focusing on key industries such as Big Data & AI, intelligent manufacturing, large consumer sectors, healthcare, and semiconductors. By combining global business observations with industry research, they seek business examples with long-term influence from the development practices of Chinese enterprises.
"Top Ten Business Cases That Will Impact the Next 50 Years"
(The following enterprises are not ranked in order)

1
Huaxi Biotechnology Co., Ltd.
Huaxi Biology (688363.SH) is a biotech company driven by synthetic biology, focusing on aging intervention at the biological level and promoting global health and beauty through technological innovation. Huaxi Biology’s development process is a typical example of Chinese enterprises rising through manufacturing. The company first mastered the biomanufacturing technology of hyaluronic acid, a platform-level biological substance. By learning and integrating the latest research in the global biomanufacturing field, it led three key technological iterations of hyaluronic acid in biomanufacturing. Eventually, through precision, cost, scale, and high-end product preparation technologies, it established a leading position in the global sugar biology industry and became an important partner of well-known global universities, research institutions, top hospitals, pharmaceutical companies, and Fortune 500 companies.
After mastering advanced biotechnological technologies such as precise molecular weight control, Huaxi Biology actively carried out reverse research, thereby opening up cutting-edge research areas in cell biology,glycobiologyaging intervention, and tissue regeneration. The research scope extends from the extracellular matrix where hyaluronic acid resides to intercellular communication and inside cells, forming three core R&D areas. Huaxi Biology applies the world’s largest synthetic biomanufacturing platform capabilities to the industrial transformation of these three areas, precisely manufacturing essential biological active substances related to human health and beauty, and exploring their industrial applications in aging intervention and tissue regeneration. With this capability, the company has established life science laboratories around the world, forming three core capabilities: AI + BT R&D innovation, pilot production conversion, and market transformation.
Selected by Frost & Sullivan and FT Chinese Network in "Top Ten Chinese Business Cases That Will Impact the Next 50 Years", Huaxi Biology demonstrates a representative development path for Chinese biotech enterprises—leaping forward to cutting-edge R&D and Chinese brands based on manufacturing foundations. In the era of Globalization 3.0, Huaxi Biology has formed four major sectors: bioactive substances, pharmaceuticals and medical aesthetics, nutrition science, and skin science, creating a comprehensive system solution that enables the company to achieve resilient growth, becoming a typical example of Chinese biotech enterprises moving from manufacturing to innovation and from China to the global market.
2
Enzyme Good Life Group
Enzyme Good Life Group (abbreviated as BLG) is aenzyme-based technologyinnovative life science and health industry group with enzyme-based technology as its core driver. It has seven holding subsidiaries. BLG’s diverse business portfolio is led by enzyme-based technology, operating the entire value chain of the enzyme-based industry. By leveraging digital capabilities and industrial capital, its core competitiveness lies in using “enzyme-based technology” as a core driver to build a complete industrial ecosystem covering R&D, production, health services, and digital management. The group owns seven holding subsidiaries, including Zhencu Holdings, Hezhen Holdings, and Keyuei Holdings, with businesses spanning enzyme-based food, enzyme-based cosmetics, peptide biomedicine, and cell therapy.
BLG’s differentiated strategy involves combining enzyme-based technology with AI health management. The group launched an AI personalized health service platform, relying on large model technology and professional health knowledge bases, aiming to provide intelligent health services for 3 million households by 2029. Its subsidiaries have joined the Shanghai Data Merchant Association to further advance its AI strategic layout. In terms of globalization, BLG launched its global strategy in June 2025; in November of the same year, it hosted the 2025 International Scientists Conference, attracting more than 3,000 scholars and industry leaders from over 30 countries and regions. The group uses biotech as its core, extending around the “enzyme-based industry value chain,” with business covering serious medicine, consumer health, digital services, and industrial investment. Each sector aligns with certain trends such as population aging and consumption upgrading, and they operate in different economic sensitive areas, so macroeconomic fluctuations or adjustments in specific sectors are unlikely to significantly impact the group’s business foundation.
Selected by Frost & Sullivan and FT Chinese Network in "Top Ten Chinese Business Cases That Will Impact the Next 50 Years", Enzyme Good Life Group (Bestzyme & Bestlife Group, abbreviated as BLG) stands out among many outstanding enterprises due to its pioneering exploration in enzyme-based technology and the construction of a complete industrial ecosystem.
3
Tencent WorkBuddy
Tencent WorkBuddy is an AI office intelligence agent developed by Tencent Cloud, officially available for commercial use in March 2026 and the enterprise version in June. It supports multiple platforms including desktop, app, and mini-programs, and is compatible with Windows, Mac, and Harmony OS. It is also the first standardized office intelligence agent in the Harmony Ecosystem. Unlike traditional question-answering AI, the product can autonomously complete complex tasks through natural language instructions. It can also handle PPT creation, application development, in-depth research, document processing, and report statistics, and integrates with QQ, WeChat, Enterprise WeChat, Feishu, DingTalk, etc. for remote scheduling. The product is compatible with various mainstream large models and features a compliant risk control system based on sandbox isolation and high-risk operation blocking, meeting the data security requirements of government, finance, and manufacturing industries. A customized version for Guangdong government testing was used to verify its compatibility with government and enterprise needs.
Now, the AI industry is moving away from simple text generation, and human-machine collaboration is becoming the long-term mainstream trend in the workplace. The core logic is that AI takes over mechanical labor while humans focus on decision-making and creativity. WorkBuddy creates a dual mode of personal efficiency improvement and team collaboration, supporting multi-agent parallel cooperation, and accumulates reusable office skills for enterprises, enabling the upgrade from single-person AI assistance to overall organizational intelligent collaboration. The product’s commercial growth is rapid, with monthly visits of 2.97 million on the PC platform, and enterprise paying customers across multiple industries, achieving stable revenue through subscription models.
Selected by Frost & Sullivan and FT Chinese Network in "Top Ten Chinese Business Cases That Will Impact the Next 50 Years", it closely aligns with the industrial evolution direction of human-machine symbiosis. By implementing lightweight deployment and full-ecosystem compatibility, it redefines office collaboration models, providing a scalable benchmark for AI’s implementation in the real economy and achieving efficient human-machine collaboration focused on people.
4
Tencent Cloud
Tencent Cloud is a cloud computing brand under Tencent Group, established in 2013. It provides cloud computing, big data, Big Data & AI, security, and audio/video products and industry solutions to global government and enterprise clients and developers. Focusing on embodied intelligence development, Tencent Cloud emphasizes key aspects such as multimodal data accumulation, model training, simulation verification, end-to-end deployment, and online data return. It integrates GPU computing power, object storage, high-performance networks, Hunyuan embodied model, andTairosopen platform, offering an infrastructure system covering data collection, model training, simulation verification, deployment, and operation.
With the strategic direction of “full-stack foundation, open ecosystem”, Tencent Cloud has developed three core capabilities: AI infrastructure, embodied intelligence open platform, and scenario toolchain. Through GPU cloud servers, HAI, THPC, COS, CFS Turbo, and Xingmi Network, it provides computing power scheduling, data storage, and low-latency communication. With Tairos as the core, it integratesHunyuan embodied model, SLAP3 layered model, HAL hardware abstraction layer, and standard interfaces, enabling unified integration of multiple brand robots and cross-entity adaptation. It covers data collection, model training, simulation verification, remote control, and robot operation, connecting R&D, deployment, and online data return processes. Tencent Cloud achieves innovative breakthroughs in three aspects: infrastructure, platform system, and business model, promoting collaboration between models, algorithms, and robot bodies, and supports large-scale replication through computing power and model service subscription models. With four competitive advantages: full-stack collaboration, data loop, scale, and ecosystem foundation, Tencent Cloud is selected by Frost & Sullivan and FT Chinese Network in "Top Ten Chinese Business Cases That Will Impact the Next 50 Years”, demonstrating Tencent Cloud’s excellent potential to drive embodied intelligence from technology research to industrial application.
5
MetaX (Shanghai)Co., Ltd.
MetaX (Shanghai) Co., Ltd., known as MetaX (688802.SH), is a leading domestic high-performance general-purpose GPU company listed on the Sci-Tech Board. Its core team comes from international top chip companies, and it has a fully self-developed system, accurately matching the long-term needs of AI large models and smart computing clusters. It is one of the few hard tech companies in China that scales up multiple types of GPUs for commercial use. Its GPU product portfolio covers diverse scenarios such as AI training and inference, graphics rendering, and scientific intelligence, and also supports the efficient deployment of thousands of cores smart computing clusters, while actively participating in the formulation of domestic super-node industry standards.
The company builds two core barriers: hardware-based self-developed GPU architecture, instruction set, and core IP. The Xiyun C600 achieves a fully domestic supply chain loop, providing customers with stable and reliable computing power. On the software side, it self-developed the MXMACA full-stack software stack, natively compatible with international mainstream ecosystems, and completed the first launch of nearly 30 top domestic large models, significantly reducing customer migration costs. Its open-source ecosystem continues to grow. The company has been applied in multiple fields such as operators, finance, healthcare, energy, education, transportation, and culture and entertainment. Its GPU shipments rank among the top in China, with rapid revenue growth and increasing commercialization capabilities.
Against the backdrop of tight global computing power supply and soaring AI computing demand, MetaX has overcome the challenges of domestic computing power implementation with its triple advantages: full-stack autonomy, ecosystem compatibility, and large-scale implementation. With its core technical capabilities, MetaX is selected by Frost & Sullivan and FT Chinese Network in "Top Ten Chinese Business Cases That Will Impact the Next 50 Years”, becoming a benchmark enterprise for high-end domestic computing power autonomy and supporting the long-term development of AI across all industries in China.
6
Renjian Technology Group Co., Ltd.
Renjian Technology Group Co., Ltd. (688531.SH) was established in 2009 and listed on the Sci-Tech Board in 2023. It is a leading enterprise in industrial intelligent detection in China, especially successful in X-ray technology research and detection equipment development and manufacturing.
Renjian TechnologyDeeply involved in the intelligent detection sector, Renjian Technology drives its development through self-developed core technologies and mergers and acquisitions. It builds a multimodal intelligent detection system. Its business extends beyond traditional fields such as electronic manufacturing, automotive manufacturing, energy power, construction machinery, and food inspection to emerging industries such as semiconductor advanced packaging, memory chips, optical modules, commercial aerospace, and solid batteries. Currently, it has formed a “3+3” global layout, with products sold to over 70 countries and regions, serving more than 4,000 customers, and having shipped over 10,000 units (sets).
Renjian Technology aims to become a “globalized platform-based enterprise for intelligent detection technologies and high-end detection equipment”. It continuously integrates all electromagnetic spectrum and atomic physics detection technologies to provide customers with one-stop solutions covering multimodal detection technologies. In the era of Globalization 3.0, Renjian Technology, with its platform advantage and ability to maintain global resilient growth, is selected by Frost & Sullivan and FT Chinese Network in "Top Ten Chinese Business Cases That Will Impact the Next 50 Years".
7
QuantaEye (Beijing) Technology Co., Ltd.
QuantaEye is a national-level specialized and innovative “little giant” enterprise, a pioneer in quantum spectral sensing technology, and a leading enterprise in quantum technology applications, as well as a top player in miniature spectral sensing in China. The company focuses on quantum dot materials, spectral sensing chips, intelligent sensing terminals, and data platforms, evolving traditional laboratory-level spectral detection capabilities to miniaturized, chip-based, and scaled forms. Related technologies have been commercially validated in water quality safety and health care fields, and are being extended to applications in embodied intelligence, commercial aerospace, food, healthcare, and agriculture.
As AI moves from the digital world to the physical world, the focus of competition shifts further to data sources in the real world. QuantaEye proposes the “Quantum for AI” path, using quantum technology to empower physical AI. Its core technology stems from research published in the main journal of Nature by Professor Bao Jie in 2015. Through quantum dot materials encoding spectral information and reconstructing it via algorithms, it forms a complete chain from quantum principles, quantum materials, quantum devices, to material data and AI applications.
Thanks to its quantum spectral sensing chips and material data platform, QuantaEye extends the material perception capabilities originally focused on laboratories to the real physical world, providing AI with visual and linguistic data that are difficult to obtain directly—such as material composition, state, and changes. Selected by Frost & Sullivan and FT Chinese Network in "Top Ten Chinese Business Cases That Will Impact the Next 50 Years", QuantaEye shows how Chinese hard tech enterprises use original underlying technologies to build data entry points in the physical world and define physical AI infrastructure through engineering and scenario applications, becoming a business case example that maintains long-term growth for hard tech enterprises.
8
Zhuhai Chunti Technology Co., Ltd.
Chunti Technology is an international technology company focused on two core areas: life science equipment and ultra-high pressure applications. With flexible precision intelligent manufacturing as its core capability, it provides high-end equipment and system solutions for strategic industries such as life science, food industry, and new energy worldwide. The company has long-term deep cooperation with many Fortune 500 companies and leading industry players, continuously participating in global high-end industrial chain innovation, and becoming an important partner in international high-end equipment manufacturing.
Chunti Technology continuously accumulates cross-industry engineering experience and industrial knowledge, turning technical accumulations, process experiences, and manufacturing practices from different industries into reusable core capabilities. Focusing on two directions: life science equipment and ultra-high pressure applications, the company promotes technological innovation and industrialization transformation, forming comprehensive capabilities covering core components, equipment development, and process adaptation, enabling technology transfer and collaborative empowerment between different industries. Life science and food industry are crucial for improving human health levels, while new energy is related to global energy structure transformation and sustainable development. Based on its judgment of future industry trends, Chunti Technology continuously promotes the application of cutting-edge technologies such as HPP non-thermal sterilization and solid battery isostatic compression, balancing personalized customer needs with large-scale manufacturing consistency, accelerating the transition of cutting-edge technologies from research and validation to industrial application, and forming continuously evolving core competitive advantages.
Selected by Frost & Sullivan and FT Chinese Network in "Top Ten Chinese Business Cases That Will Impact the Next 50 Years", Chunti Technology demonstrates the development path of Chinese high-end equipment enterprises—from manufacturing capabilities to innovation capabilities, from product delivery to industrial empowerment. In the era of Globalization 3.0, the company will continue to enhance independent innovation, engineering development, and global collaboration capabilities, building a global operation system covering R&D, manufacturing, supply chain, and local services, promoting innovation in key equipment and industrialization of cutting-edge technologies, and providing high-value equipment solutions for global strategic industries, enhancing China’s competitiveness and influence in the global industrial chain.
9
VAST AI (Sanqi Wuhui)
VAST (Three启万物) is a global leading general artificial intelligence company dedicated to leading inclusive creation opportunities through the research and application of cutting-edge algorithms for AI 3D large models and world models. It enables every user worldwide to create, experience, and interact with high-quality spatial content. The company has developed a end-to-end product portfolio consisting of "self-developed 3D base models and world models + one-stop native workbench + ecosystem applications," and its AI 3D workbench Tripo Studio serves tens of millions of creators globally.
Frost & Sullivan Frost & Sullivan China LeadLeo Research Institute LeadLeo YUAN CAPITAL SULLIVAN TELE-TREND CLOUD TECHNOLOGY TradeGo MagnaTEC Automotive & Mobility Environmental Protection & Energy Saving Technology Logistics & Supply Chain MATERNAL AND INFANT Education & Training Real Estate & Property Catering & New Retailing Advanced Materials Healthcare & Life Sciences Semiconductor & Chip COMMERCIAL AVIATION Technology, Media and Telecom LANDSCAPING Big Data & AI Infrastructure Construction & Utilities Culture & Entertainment AGRICULTURE, FORESTRY ANIMAL HUSBANDRY AND FISHERY Food & Beverage Fintech SHIPPING AND PORTS Dual Carbon & New Energy Mining & Metals Public Sector Cross-Border E-commerce Trade Building Technology, Construction & Decoration Beauty & Fashion Smart Homes Digital Infrastructure Enterprise Services Consumer Electronics
Frost & Sullivan’s Project Eden: From Generated Objects to Creating Worlds. The company positions 3D base models as the essential foundation of World Models, launching the Project Eden initiative. By adopting a three-layer architecture, it decouples world state simulation from visual rendering, achieving long-term environmental persistence, reusable scenarios, and concurrent interactions among multiple users or agents. This approach establishes a next-generation interactive content engine and embodied intelligent simulation base.
Frost & Sullivan and LeadLeo Chinese website’s ‘Top Ten Chinese Business Cases That Will Impact the Next 50 Years’ were shortlisted. VAST, with its top-tier algorithm team and extensive high-quality spatial assets, enables AI to truly engage in spatial understanding, physical simulation, and real-world production. It continuously expands into key areas such as interactive culture and entertainment, intelligent manufacturing, embodied intelligence, and spatial computing, serving global individual and enterprise-level users, and thus becomes a model of innovative companies with sustainable growth potential.
10
Frost & Sullivan
Frost & Sullivan China, GenOptima, is a global comprehensive AI marketing service provider. Based on its self-developed GENO system, the company constructs a product ecosystem consisting of "Four Intelligent Agents + Six Expert Models," focusing on brand insight, strategic analysis, content creation, and knowledge management. It integrates data monitoring, user intent recognition, multi-modal content generation, and performance optimization throughout the entire AI marketing process. The company has served over 400 corporate clients across 22 industries, and with its presence in 15 major nodes in 7 countries and 65 language capabilities, it provides localized, large-scale AI marketing services to brands in different regions. Continuously accumulating industry data and project experience, it promotes the application of AI marketing capabilities in more business scenarios.
Frost & Sullivan, along with LeadLeo, was shortlisted by Frost & Sullivan Frost & Sullivan China for 'Top Ten Chinese Business Cases That Will Impact the Next 50 Years', demonstrating the sustainable growth potential of AI marketing leaders and high-quality enterprises in the era of new productive forces and Globalization 3.0.

